Phytochemical investigation of the chloroformic extract of aerial parts of Salvia persepolitana Boiss.

Habibi, Z.; Ghahremanzadeh, R.; Yousefi, M.

doi:10.22092/ijmapr.2014.10710

Document Type : Research Paper

Authors

¹ Department of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, Iran

² Nanobiotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), Tehran, Iran

https://doi.org/10.22092/ijmapr.2014.10710

Abstract

The aerial parts of Salvia persepolitana Boiss. were collected during the flowering stage from IlamProvince. Purification of chloroform extract of S. persepolitana was carried out by column chromatography on silica gel with a gradient of n-hexan/ethyl acetate. At the end of chromatography, the column was eluted by methanol. Further purification was carried out by column chromatography (smaller columns) and thin layer chromatography (glass plates) in n-hexane–ethyl acetate as solvent for several times and yielded pure compounds. The structure of purified natural products was elucidated by using Nuclear Magnetic Resonance (NMR) spectroscopy and Mass spectrometry. The chloroform extract of S. persepolitana yielded two known diterpenoids as manool and sclareol and one known flavonoid namely ladanein. The amount of purified sclareol was 3% (18g) of the total plant weight, so S. persepolitana can be a good sourse for sclareol.

Keywords

References

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Iranian Journal of Medicinal and Aromatic Plants Research

Phytochemical investigation of the chloroformic extract of aerial parts of Salvia persepolitana Boiss.

References

References

Volume 30, Issue 5 - Serial Number 67
December 2014
Pages 724-732

Phytochemical investigation of the chloroformic extract of aerial parts of Salvia persepolitana Boiss.

References

References

Volume 30, Issue 5 - Serial Number 67December 2014Pages 724-732

Volume 30, Issue 5 - Serial Number 67
December 2014
Pages 724-732