H. Mostaanzadeh; E. Honarmand; S. Reis Mirzaei; A.R. Moradzadeh; M. Hoseinzadeh
Abstract
Renal stones is a common disease of the urinary tract that many people suffer from it. Although there are many herbal and chemical drugs for the prevention and treatment of kidney stones in recent years, there is no effective and safe drug treatment that can lead to complete treatment and prevention ...
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Renal stones is a common disease of the urinary tract that many people suffer from it. Although there are many herbal and chemical drugs for the prevention and treatment of kidney stones in recent years, there is no effective and safe drug treatment that can lead to complete treatment and prevention of these diseases. Today, the use of herbal products is considered by researchers because of the harmful and side effects of chemical drugs. This research was carried out with the purpose of determining the herbal tea effect of leaf and stem of Apium graveolens L. and Kelussia odoratissima odoratissima Mozaff. on the formation and dissolution of calcium oxalate. In order to study the dissolution and precipitation of calcium oxalate salt, electrochemical and classic analytical methods were used. The experimental results of complexometery and conductometery techniques reveal that these herbal teas have a good effect on the dissolution and prevention of formation of calcium oxalate stone (P<0.05). According to the findings of this study, these herbal teas could be a good choice for treatment diseases and to prevent calcium oxalate formation in people disposed to kidney stones.
M. Ramezani; S. Nasri; N. Yassa
Volume 24, Issue 4 , February 2009, , Pages 437-443
Abstract
medicine, in present study aqueous and hexane extracts were evaluated to find effective fractions. For induction of inflammation xylene-induced ear edema were used. Male NMRI mice were divided into three groups: positive control (dexamethason 15mg/kg), negative control (normal saline), and experimental ...
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medicine, in present study aqueous and hexane extracts were evaluated to find effective fractions. For induction of inflammation xylene-induced ear edema were used. Male NMRI mice were divided into three groups: positive control (dexamethason 15mg/kg), negative control (normal saline), and experimental groups. Experimental groups were injected by 100, 200, 300, 400 and 500mg/kg of aqueous and hexane extracts intraperitoneally. To find effective constituents of extract, TLC (thin layer chromatography) was performed. Results have shown significant anti-inflammatory effects of both extracts (100-500mg/kg doses) with control, and there was not significant difference with dexamethason. Data show potent anti-inflammatory effects of aqueous and hexane extracts even with low doses which may be due to existence of flavonoid, phthalid and coumarins in Apium graveolens seeds.
M. Roghani; T. Baluchnejadmojarad; M. Ramazani
Abstract
Diabetes mellitus is one of the most common endocrine disorders which accompanies multiple metabolic abnormalities. On the other hand, Apium graveolens L. (AG) has been known to reduce lipid peroxidation and lower some serum lipids in an animal model of hyperlipidemia. Therefore, the effect of chronic ...
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Diabetes mellitus is one of the most common endocrine disorders which accompanies multiple metabolic abnormalities. On the other hand, Apium graveolens L. (AG) has been known to reduce lipid peroxidation and lower some serum lipids in an animal model of hyperlipidemia. Therefore, the effect of chronic oral administration of this plant on serum glucose, triglyceride, total cholesterol, and HDL- and LDL-cholesterol level of diabetic rats was investigated. For this purpose, male Wistar rats (n = 40)(270-320 g; 3.5-4.5 months old) were randomly divided into 4 groups, i.e. control, AG-treated control, diabetic, and AG-treated diabetic groups. The treatment groups received oral administration of plant-mixed pelleted food (6.25%, w/w) for 6 weeks. Serum glucose, triglyceride, total cholesterol, LDL- and HDL- cholesterol levels were determined before the study, and at the 3rd and 6th weeks after the study. There was a significant reduction (p<0.01) in weight of animals in AG-treated and untreated diabetic groups after 6 weeks as compared to control one and the existing difference between these two groups were not significant. In addition, serum glucose level in diabetic group increased 6 weeks after the experiment as compared to the data a week before the study (P<0.001) and AG treatment of diabetic rats only had a slight and non-significant effect. Furthermore, triglyceride level in diabetic group increased 6 weeks after the experiment in comparison with related data one week before the study (P<0.05) and there was a significant lower level of triglyceride in AG-treated diabetic rats (p<0.01). Furthermore, a similar significant reduction was obtained for AG-treated-diabetic group compared to diabetic group regarding serum cholesterol level (p<0.05). On the other hand, HDL- and LDL- cholesterol levels were significantly higher (p<0.05) and lower (p<0.01) in AG-treated diabetic group compared to untreated diabetic group, respectively. As a result, oral chronic administration of AG has no significant hypoglycemic effect but leads to appropriate changes in blood lipid profile.
