Document Type : Research Paper

Authors

• Z. Habibi ¹
• M. Yousefi ²

¹ Department of Chemistry, Faculty of Sciences, Shahid Beheshti University, Tehran, Iran

² Ph.D. Student, Department of Chemistry, Faculty of Sciences, Shahid Beheshti University, Tehran, Iran

Abstract

The chemical constituents of essential oil and the extract of Codonocephalum stenocalathium Rech. f. were investigated. The oil of the aerial parts was obtained with hydrodistillation by Clevenger apparatus and analyzed by gas chromatography/mass spectrometry (GC/MS). Twenty-seven compounds, representing 70.9% of oil were identified. ‏The main constituents were (E)-nuciferol (10.4%), geranyl-n-propionate (6.4%) and (Z)-lanceol acetate(4.7%). The chloroform extract of C. stenocalathium yielded two known compounds as pseudotaraxasterol acetate and ilicic acid. The structures of these natural products were elucidated by using ¹H and ¹³C Nuclear Magnetic Resonance (NMR) spectroscopy. The antibacterial activity of the crude extract was examined against three Gram-positive and three Gram-negative bacteria. The extract showed inhibitory effects on the growth of bacteria especially against Staphylococcus aureus, Bacillus subtilis and Escherichia coli.
 

Keywords

• Codonocephalum stenocalathium Rech. f
• essential oil
• chloroform extract
• antimicrobial effect