Evaluation the effects of aqueous and alcoholic extracts of  Myrtus communis L. on tachyzoites of Toxoplasma gondii in vitro

Mirzaian, H.; Ghaffarifar, F.; Sadraei, J.; Abdoli, A.

doi:10.22092/ijmapr.2019.114713.2081

Document Type : Research Paper

Authors

¹ M.Sc. graduate, Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

² Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

³ Department of Parasitology and Mycology, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran

https://doi.org/10.22092/ijmapr.2019.114713.2081

Abstract

Toxoplasmosis is one of the most common zoonotic infections worldwide. The aim of this study was to evaluate anti-Toxoplasma gondii activities of aqueous and alcoholic extracts of Myrtus communis L. in vitro. In this study, effects of aqueous and alcoholic extracts of M. communis on T. gondii-infected mouse macrophages were evaluated by MTT and direct method. The results showed that the aqueous extract of M. communis with concentrations of 12.5 and 25 µg/ml had the highest anti-T. gondii activity (87 and 81%), while their lethal effect on non-infected macrophage was less than other concentrations. The present study showed that the aqueous and alcoholic extracts of M. communis have a considerable inhibitory effect on Toxoplasma gondii tachyzoites and parasite intracellular proliferation in vitro.

Keywords

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Iranian Journal of Medicinal and Aromatic Plants Research

Evaluation the effects of aqueous and alcoholic extracts of Myrtus communis L. on tachyzoites of Toxoplasma gondii in vitro

References

References

Volume 35, Issue 2 - Serial Number 94
May and June 2019
Pages 276-290

Evaluation the effects of aqueous and alcoholic extracts of Myrtus communis L. on tachyzoites of Toxoplasma gondii in vitro

References

References

Volume 35, Issue 2 - Serial Number 94May and June 2019Pages 276-290

Volume 35, Issue 2 - Serial Number 94
May and June 2019
Pages 276-290