Iranian Journal of Medicinal and Aromatic Plants Research

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Essential oil diversity of 21 populations from Iranian endemic species Nepeta kotschyi Boiss.

Document Type : Research Paper

Authors

1 Ph.D. Student, Agriculture College, Tarbiat Modares University, Tehran, Iran

2 Research Institute of Forests and Rangelands, Agricultural Research Education and ExtensionOrganization (AREEO), Tehran, Iran

3 Horticulture Department, Agriculture College, Tarbiat Modares University, Tehran, Iran

4 Research Institute of Forests and Rangelands, Agricultural Research Education and Extension Organization (AREEO), Tehran, Iran

Abstract

The genus Nepeta is one of the largest genera of the Lamiaceae family, and Iran, particularly, is one of the main centers of origin of this genus. Nepetalactones and flavonoids were reported as major constituents of Nepeta species, and the main cause of their medicinal value and biological properties. There are lots of reports related to biological activities of secondary metabolites of genus Nepeta showing the importance of this genus. In this work, the essential oil (EO) diversity of 21 wild populations from Nepeta kotschyi Boiss., Iranian endemic species, was investigated. For removing the environmental effect, the seeds of populations were planted in one place. Plant aerial parts were harvested at full flowering stage, and after shade-drying, their EO was extracted by hydrodistillation method. EO was quantitatively and qualitatively analyzed by GC and GC/MS. After botanical study and EO analysis, it was revealed that the populations were from two different varieties. Two populations including buyer-ahmad1 and Buyer-Ahmad2, were from N. kotschyi var. kotschyi, and others were stood in N. kotschyi var. persica. Twenty-four components were characterized in the EO of N. kotschyi. The highest amount of EO yield (w/w) was obtained in populations of var. kotschyi (0.5-0.7%). Three main chemotypes were identified among populations of var. persica based on the main component(s) of EO, including a containing NepI (4aα,7α,7aα-nepetalactone), b containing NepII (4aα,7α,7aβ-nepetalactone) and cubenol, and c containing geranyl acetate and cubenol. Except of semirom and Taft5 which were stood in b-chemotype, and Taft4 which was placed in c-chemotype, other populations of var. persica, also populations of var. kotschyi, were stood in a-chemotype. In addition, based on the main component of EO, the populations of var. kotschyi were put in a-chemotype. In a-chemotype, the amount of NepI was obtained between %53.9 (Chelgard) and %84.8 (Buyer-Ahmad2), and NepII was measured between %1 (Taft1) and %13.7 (Chelgard). In b-chemotype, the amount of NepI was measured between %0.3 (Taft5) and %4.9 (Semirom), and NepII was obtained between %13.4 (Taft5) and 44.7% (Semirom). NepIII (4aα,7β,7aα-nepetalactone) (1.3-3.3%) was characterized only in the EO of var. Kotschyi populations.

Keywords

References
- Adams, R.P., 2004. Identification of Essential Oil Components by Gas Chromatography/Quadrupole Mass Spectroscopy. Allured Publishing Corp., Carol Stream, USA, 456p.
- Akbay, P., Calis, I., Ündeger, Ü., Basaran, N. and Basaran, A.A., 2002. In vitro immunomodulatory activity of verbascoside from Nepeta ucrainica L. Phytotherapy Research, 16(6): 593-595.
- Aydin, S., Demir, T., Ozturk, Y. and C. Baser, K.H., 1999. Analgesic activity of Nepeta italica L. Phytotherapy Research, 13: 20-23.
- Bernath, J., 2002. Strategies and recent achievements in selection of medicinal and aromatic plants. Acta Horticulture, 576: 233-238.
- Dabiri, M. and Sefidkon, F., 2003a. Chemical composition of Nepeta crassifolia Boiss. & Buhse oil from Iran. Flavour and Fragrance Journal, 18(3): 225-227.
- Dabiri, M. and Sefidkon, F., 2003b. Chemical composition of the essential oil of Nepeta racemosa from Iran. Flavour and Fragrance Journal, 18(2): 157-158.
- Esmaeili, A., Rustaiyan, A., Masoudi, S. and Nadji, K., 2006. Composition of the essential oils of Mentha aquatica L. and Nepeta meyeri Benth. from Iran. Journal of Essential Oil Research, 18(3): 263-265.
- Formisano, C., Rigano, D. and Senatore, F., 2011. Chemical constituents and biological activities of Nepeta species. Chemistry and Biodiversity, 8(10): 1783-1818.
- Ghannadi, A., Aghazari, F., Mehrabani, M., Mohagheghzadeh, A. and Mehregan, I., 2003. Quantity and composition of the SDE prepared essential oil of Nepeta macrosiphon Boiss. Iranian Journal of Pharmaceutical Research, 2(2): 103-105.
- Gkinis, G., Tzakou, O., Iliopoulou, D. and Roussis, V., 2003. Chemical composition and biological activity of Nepeta parnassica oils and isolated nepetalactones. Zeitschrift für Naturforschung,
58(-10): 681-686.
- Hammer, Ø., Harper, D.A.T. and Ryan, P.D., 2001. PAST: paleontological statistics software package for education and data analysis. Palaeontologia Electronica, 4(1): 1-9.
- Hussain, J., Jamila, N., Gilani, A., Abbas, G. and Ahmed, S., 2009. Platelet aggregation, antiglycation, cytotoxic, phytotoxic and antimicrobial activities of extracts of Nepeta juncea. African Journal of Biotechnology, 8(6): 935-940.
- Hussain, J., Ullah Khana, F., Ullah Khan, I., Ullah, R., Muhammad, Z., Khan, N., Hussain, T., Ullah, M., Rahim, H. and Ullah Khan, A., 2010. Antifungal and immunomodulatory potential of Nepeta suavis. American-Eurasian Journal of Agricultural & Environmental Sciences, 7(6): 689-692.
- Javidnia, K., Miri, R., Safavi, F., Azarpira, A. and Shafiee, A., 2002. Composition of the essential oil of Nepeta persica Boiss. from Iran. Flavour and Fragrance Journal, 17(1): 20-22.
- Kahkeshani, N., Razzaghirad, Y., Ostad, S.N., Hadjiakhoondi, A., Shams Ardekani, M.R., Hajimehdipoor, H., Attar, H., Samadi, M., Jovel, E. and Khanavi, M., 2014. Cytotoxic, acetylcholinesterase inhibitor and antioxidant activity of Nepeta menthoides Boiss & Buhse essential oil. Journal of Essential Oil Bearing Plants, 17(4): 544-552.
- Kraujalis, P., Venskutonis, P.R. and Ragazinskiene, O., 2011. Antioxidant activities and phenolic composition of extracts from Nepeta plant species. Foodbalt, 79-83.
- Mahboubi, M., Kazempour, N., Ghazian, F. and Taghizadeh, M., 2011. Chemical composition, antioxidant and antimicrobial activity of Nepeta persica Boiss. essential oil. Herbapolonica, 57(1): 62-71.
- Matloubi Moghaddam, F. and Hosseini, M., 1996. Composition of the essential oil from Nepeta crassifolia Boiss. & Buhse. Flavour and Fragrance Journal, 11(2): 113-115.
- Miceli, N., Taviano, M.F., Giuffrida, D., Trovato, A., Tzakou, O. and Galati, E.M., 2005. Anti-inflammatory activity of extract and fractions from Nepeta sibthorpii Bentham. Journal of Ethnopharmacology, 97(2): 261-266.
- Mojab, F., Nickavar, B. and Hooshdar Tehrani, H., 2009. Essential oil analysis of Nepeta crispa and N. menthoides from Iran. Iranian Journal of Pharmaceutical Sciences, 5(1): 43-46.
- Monavari, S.H.R., Shamsi Shahrabadi, M., Vahabpour, R. and Azizi, M., 2011. The effects of the anti-viral of Nepeta pungens on measles virus in laboratory environment. Ofogh-e-Danesh, 17(1): 27-33.
- Morteza-Semnani, K. and Saeedi, M., 2004. Essential oils composition of Nepeta cataria L. and Nepeta crassifolia Boiss. and Buhse from Iran. Journal of Essential Oil Bearing Plants, 7(2): 120-124.
- Mozaffarian, V., 1996. Dictionary of Iranian Plant Names. Farhang Moaser, Tehran, 740p.
- Mozaffarian, V., 2013. Identification of Medicinal and Aromatic Plants of Iran. Farhang Moaser, Tehran, 1444p.
- Mutlu, S. and Atici, O., 2009. Allelopathic effect of Nepeta meyeri Benth. extracts on seed germination and seedling growth of some crop plants. Acta Physiologiae Plantarum, 31: 89-93.
- Nadjafi, F., Koocheki, A., Honermeier, B. and
Asili, J., 2009. Autecology, ethnomedicinal and phytochemical studies of Nepeta binaludensis Jamzad a highly endangered medicinal plant of Iran. Journal of Essential Oil Bearing Plants, 12(1): 97-110.
- Nemeth, E., Bernath, J. and Hethelyi, E., 2000. Chemotypes and their stability in Achillea crithmifolia populations. Journal of Essential Oil Research, 12: 53-58.
- Nori-Shargh, D., Baharvand, B. and Deyhimi, F., 2006. The volatile constituents analysis of
Nepeta kotschyi Boiss. from Iran. Journal of Essential Oil Research, 18(3): 237-238.
- Rabbani, M., Sajjadi, S.E. and Mohammadi, A., 2008. Evaluation of the anxiolytic effect of Nepeta persica Boiss. in mice. Evidence-Based Complementary and Alternative Medicine (eCAM), 5(2): 181-186.
- Rustaiyan, A., Jamzad, M., Masoudi, S. and Ameri, N., 2006. Volatile constituents of Nepeta heliotropifolia Lam., Mentha mozaffarianii Jamzad and Ziziphora persica Bunge. three Labiatae herbs growing wild in Iran. Journal of Essential Oil Research, 18(3): 348-351.
- Rustaiyan, A., Khosravi, M., Larijany, K. and Masoudi, S., 2000a. Composition of the essential oil of Nepeta racemosa Lam. from Iran. Journal of Essential Oil Research, 12(2): 151-152.
- Rustaiyan, A., Komeilizadeh, H., Monfared, A., Nadji, K., Masoudi, S. and Yari, M., 2000b. Volatile constituents of Nepeta denudata Benth. and N. cephalotes Boiss. from Iran. Journal of Essential Oil Research, 12(4): 459-461.
- Rustaiyan, A. and Nadji, K., 1999. Composition of the essential oils of Nepeta ispahanica Boiss. and Nepeta binaludensis Jamzad from Iran. Flavour and Fragrance Journal, 14(1): 35-37.
- Safaei-Ghomi, J., Djafari-Bidgoli, Z. and Batooli, H., 2009. Volatile constituents analysis of Nepeta cataria from central Iran. Chemistry of Natural Compounds, 45(6): 913-915.
- Sajjadi, E., 2005. Analysis of the essential oil of Nepeta sintenisii Bornm. from Iran. Daru, 13(2):
61-64.
- Salehi, P., Sonboli, A., Khaligh, P. and Mirzajani, F., 2012. Essential oil composition and antioxidant activity of different extracts of Nepeta betonicifolia C.A. Meyer and Nepeta saccharata Bunge. Flavour and Fragrance Journal, 26(8): 736-743.
- Schultz, G., Simbro, E., Belden, J., Zhu, J. and Coats, J., 2004. Catnip, Nepeta cataria (Lamiales: Lamiaceae)- a closer look: seasonal occurrence of nepetalactone isomers and comparative repellency of three terpenoids to insects. Environmental Entomology, 33(6): 1562-1569.
- Sefidkon, F. and Akbarinia, A., 2003. Essential oil composition of Nepeta pogonosperma Jamzad et assadi from Iran. Journal of Essential Oil Research, 15(5): 327-328.
- Sefidkon, F., Dabiri, M. and Alamshahi, A., 2002. Analysis of the essential oil of Nepeta fissa C.A. Mey from Iran. Flavour and Fragrance Journal, 17(2): 89-90.
- Sefidkon, F. and Jamzad, Z., 2007. Essential oil composition of four Iranian Nepeta species
(N. cephalotes, N. bornmuelleri, N. mirzayanii and N. bracteata). Journal of Essential Oil Research, 19(3): 262-265.
- Sefidkon, F., Jamzad, Z. and Mirza, M., 2006. Chemical composition of the essential oil of five Iranian Nepeta species (N. crispa, N. mahanensis, N. ispahanica, N. eremophila and N. rivularis). Flavour and Fragrance Journal, 21(5): 764-767.
- Sefidkon, F. and Shaabani, A., 2004. Essential oil composition of Nepeta meyeri Benth. from Iran. Flavour and Fragrance Journal, 19(3): 236-238.
- Sonboli, A., Gholipour, A., Yousefzadi, M. and Mojarrad, M., 2009. Antibacterial activity and composition of the essential oil of Nepeta menthoides from Iran. Natural Product Communications, 4(2): 283-286.
- Sonboli, A., Salehi, P. and Allahyari, L., 2005. Essential oil composition of Nepeta involucrata from Iran. Chemistry of Natural Compounds, 41(6): 683-685.
- Sonboli, A., Salehi, P. and Yousefzadi, M., 2004. Antimicrobial activity and chemical composition of the essential oil of Nepeta crispa Willd. from Iran. Zeitschrift fur Naturforschung C, 59c: 653-656.
- Tepe, B., Daferera, D., Tepe, A.S., Polissiou, M. and Sokmen, A., 2007. Antioxidant activity of the essential oil and various extracts of Nepeta flavida Hub.-Mor. from Turkey. Food Chemistry, 103: 1358-1364.
- Zhu, J.J., Berkebile, D.R., Dunlap, C.A., Zhang, A., Boxler, D., Tangtrakulwanich, K., Behle, R.W., Baxendale, F. and Brewer, G., 2011. Nepetalactones from essential oil of Nepeta cataria represent a stable fly feeding and oviposition repellent. Medical and Veterinary Entomology, 26: 131-138.
- Zomorodian, K., Saharkhiz, M.J., Rahimi, M.J., Shariatifard, S., Pakshir, K. and Khashei, R., 2013. Chemical composition and antimicrobial activities of essential oil of Nepeta cataria L. against common causes of oral infections. Journal of Dentistry, Tehran University of Medical Sciences, 10(4):
329-337.
Iranian Journal of Medicinal and Aromatic Plants Research
Volume 32, Issue 2 - Serial Number 76
June 2016
Pages 189-202
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